| Name | Paprotrain |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5041 |
| Prices | $75.00, $315.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 57046-73-8 |
| Chemical Name | (Z)-α-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile |
| Formula | C16H11N3 |
| Molecular Weight | 245.28 |
| Purity | >99 % |
| Description | Reversible, non-ATP competitive inhibitor of mitotic kinesin-like protein 2 (MKLP-2) (K i = 3.4 μ M). Inhibits the basal ATPase activity of MKLP-2 (IC 50 = 1.35 μ M). Exhibits selectivity for MKLP-2 over 12 other members of the kinesin superfamily, including the closely-related MKLP-1. Cell permeable. |
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