Paroxetine maleate

Name Paroxetine maleate
Supplier Tocris Bioscience
Catalog 4161
Prices $129.00, $535.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 64006-44-6
Chemical Name (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-piperidinemaleate
Formula C19H20FNO3.C4H4O4
Molecular Weight 445.44
Purity >99 %
Description Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (K i = 0.05 nM). K i values are 1.1, 350 and 1100 nM for inhibition of [ 3 H]-5-HT, [ 3 H]-l-NA and [ 3 H]-DA uptake respectively. Displays minimal affinity for α 1 -, α 2 - or β -adrenoceptors, 5-HT 2A , 5-HT 1A , D 2 or H 1 receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (K i = 42 nM). Antidepressant and anxiolytic in vivo .
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