| Name | PB 28 dihydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2006 |
| Prices | $139.00, $585.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 172907-03-8 |
| Chemical Name | 1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazinedihydrochloride |
| Formula | C24H38N2O.2HCl |
| Molecular Weight | 443.5 |
| Purity | >99 % |
| Description | High affinity σ 2 receptor agonist (K i values are 0.8 and 15.2 nM for σ 2 and σ 1 receptors respectively) that displays minimal affinity at other receptors. Inhibits electrically evoked twitch in guinea pig bladder and ileum (EC 50 values are 2.62 and 3.96 μ M respectively). Displays antiproliferative and cytotoxic effects in SK-N-SH neuroblastoma and C6 glioma cells. |
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