PD 123319 ditrifluoroacetate

• Supplier: Tocris Bioscience
• Catalog: 2830
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 130663-39-7
• Chemical Name: 1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylicacidditrifluoroacetate
• Formula: C31H32N4O3.2CF3CO2H
• Molecular Weight: 736.67
• Purity: >99 %
• Description: Potent, selective, non-peptide angiotensin AT 2 receptor antagonist. IC 50 values are 34 and 210 nM in rat adrenal tissue and brain respectively.

Product References

Synthesis and structure-activity relationships of a novel series of non-peptide - Synthesis and structure-activity relationships of a novel series of non-peptide

Blankley CJ, Hodges JC, Klutchko SR, Himmelsbach RJ, Chucholowski A, Connolly CJ, Neergaard SJ, Van Nieuwenhze MS, Sebastian A, Quin J 3rd, et al.. J Med Chem. 1991 Nov;34(11):3248-60.

Modulation of angiotensin II binding affinity by allosteric interaction of - Modulation of angiotensin II binding affinity by allosteric interaction of

Boulay G, Servant G, Luong TT, Escher E, Guillemette G. Mol Pharmacol. 1992 Apr;41(4):809-15.

Induction of angiotensin II subtype 2 receptor-mediated blood pressure regulation - Induction of angiotensin II subtype 2 receptor-mediated blood pressure regulation

Tamura M, Takagi T, Howard EF, Landon EJ, Steimle A, Tanner M, Myers PR. J Hypertens. 2000 Sep;18(9):1239-46.