| Name | PD 404182 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4824 |
| Prices | $195.00 |
| Sizes | 10 mg |
| Function Type | Inhibitor |
| Cas Number | 72596-74-8 |
| Chemical Name | 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine |
| Formula | C11H11N3S |
| Molecular Weight | 217.29 |
| Purity | >98 % |
| Description | High affinity inhibitor of KDO 8-P synthase (K i = 26 nM). Also inhibits dimethylarginine dimethylaminohydrolase 1 (DDAH1). Exhibits antiangiogenic and antiviral activity in vitro . Putative antibiotic against gram-negative bacteria. |
| Supplier Page | Shop |
Ghebremariam YT, Erlanson DA, Cooke JP. J Pharmacol Exp Ther. 2014 Jan;348(1):69-76.
Chamoun-Emanuelli AM, Bobardt M, Moncla B, Mankowski MK, Ptak RG, Gallay P, Chen Z. Antimicrob Agents Chemother. 2014;58(2):687-97.