L- trans -2,4-PDC

Name L- trans -2,4-PDC
Supplier Tocris Bioscience
Catalog 1213
Prices $155.00, $645.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 64769-66-0
Chemical Name L-trans-Pyrrolidine-2,4-dicarboxylicacid
Formula C6H9NO4
Molecular Weight 159.14
Purity >97 %
Description Potent, competitive, transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™ .
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Product References

Conformationally defined neurotransmitter analogues. Selective inhibition of - Conformationally defined neurotransmitter analogues. Selective inhibition of

Bridges RJ, Stanley MS, Anderson MW, Cotman CW, Chamberlin AR. J Med Chem. 1991 Feb;34(2):717-25.

Regional differences in the inhibition of L-glutamate and L-aspartate - Regional differences in the inhibition of L-glutamate and L-aspartate

Mitrovic AD, Johnston GA. Neurochem Int. 1994 Jun;24(6):583-8.

Effects of uptake carrier blockers SK & F 89976-A and L-trans-PDC on in vivo - Effects of uptake carrier blockers SK & F 89976-A and L-trans-PDC on in vivo

Zuiderwijk M, Veenstra E, Lopes da Silva FH, Ghijsen WE. Eur J Pharmacol. 1996 Jul 4;307(3):275-82.