PE 154

• Supplier: Tocris Bioscience
• Catalog: 2207
• Prices: $235.00, $965.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 1192750-33-6
• Chemical Name: 4-[[[7-(Diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneaceticacid2-(1,2,3,4-tetrahydro-9-acridinyl)hydrazide
• Formula: C35H35N5O4
• Molecular Weight: 589.68
• Purity: >97 %
• Description: Potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC 50 values are 280 pM and 16 nM respectively). Targets and labels β -amyloid plaques in histochemical analysis.

Product References

A gorge-spanning, high-affinity cholinesterase inhibitor to explore beta-amyloid - A gorge-spanning, high-affinity cholinesterase inhibitor to explore beta-amyloid

Elsinghorst PW, Hartig W, Goldhammer S, Grosche J, Gutschow M. Org Biomol Chem. 2009 Oct 7;7(19):3940-6.

In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a - In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a

Hartig W, Kacza J, Paulke BR, Grosche J, Bauer U, Hoffmann A, Elsinghorst PW, Gutschow M. Eur J Neurosci. 2010 Jan;31(1):99-109.