Peptide YY (3-36)

• Supplier: Tocris Bioscience
• Catalog: 1190
• Prices: $189.00
• Sizes: 500 µg
• Function Type: Agonist
• Cas Number: 126339-09-1
• Formula: C176H272N52O54
• Molecular Weight: 3980.4
• Description: Y 2 selective agonist. IC 50 values are 0.11 and 1050 nM for inhibition of 125 I-PYY binding to Y 2 and Y 1 receptors respectively. Inhibits food intake and reduces weight gain in vivo . Brain penetrant.

Product References

Primary structures of PYY, [Pro(34)]PYY, and PYY-(3-36) confer different - Primary structures of PYY, [Pro(34)]PYY, and PYY-(3-36) confer different

Keire DA, Mannon P, Kobayashi M, Walsh JH, Solomon TE, Reeve JR Jr. Am J Physiol Gastrointest Liver Physiol. 2000 Jul;279(1):G126-31.

Gut hormone PYY(3-36) physiologically inhibits food intake. - Gut hormone PYY(3-36) physiologically inhibits food intake.

Batterham RL, Cowley MA, Small CJ, Herzog H, Cohen MA, Dakin CL, Wren AM, Brynes AE, Low MJ, Ghatei MA, Cone RD, Bloom SR. Nature. 2002 Aug 8;418(6898):650-4.

Characterization of blood-brain barrier permeability to PYY3-36 in the mouse. - Characterization of blood-brain barrier permeability to PYY3-36 in the mouse.

Nonaka N, Shioda S, Niehoff ML, Banks WA. J Pharmacol Exp Ther. 2003 Sep;306(3):948-53. Epub 2003 May 15.