PF 04217903 mesylate

• Supplier: Tocris Bioscience
• Catalog: 4821
• Prices: $249.00, $1,025.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 956906-93-7
• Chemical Name: 4-[1-(6-Quinolinylmethyl)-1H-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazole-1-ethanolmesylate
• Formula: C19H16N8O.CH3SO3H
• Molecular Weight: 468.49
• Purity: >98 %
• Description: Highly selective, high affinity MET inhibitor (K i = 6-7 nM against wild type c-Met). Displays >1000-fold selectivity for c-Met over a panel of 208 kinases.

Product References

Novel therapeutic inhibitors of the c-Met signaling pathway in cancer. - Novel therapeutic inhibitors of the c-Met signaling pathway in cancer.

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Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants - Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants

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Discovery of small molecule c-Met inhibitors: Evolution and profiles of clinical - Discovery of small molecule c-Met inhibitors: Evolution and profiles of clinical

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Discovery of a novel class of exquisitely selective mesenchymal-epithelial - Discovery of a novel class of exquisitely selective mesenchymal-epithelial

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