| Name | PF 06726304 acetate |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4710 |
| Prices | $159.00 |
| Sizes | 10 mg |
| Function Type | Inhibitor |
| Chemical Name | 5,8-Dichloro-2-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-7-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-1(2H)-isoquinolinoneacetate |
| Formula | C22H21Cl2N3O3.C2H4O2 |
| Molecular Weight | 506.38 |
| Purity | >97 % |
| Description | Highly potent and SAM-competitive EZH2 lysine methyltransferase inhibitor (IC 50 = 0.7 nM). Inhibits proliferation of Karpas-422 cells (non-Hodgkin's lymphoma) in vitro , and halts tumor growth and reduces intratumoral H3K27Me3 levels in mice. |
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