| Name | PF 3716556 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4279 |
| Prices | $189.00, $765.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 928774-43-0 |
| Chemical Name | 8-[[(4R)-3,4-Dihydro-5-methyl-2H-1-benzopyran-4-yl]amino]-N-(2-hydroxyethyl)-N,2-dimethyl-imidazo[1,2-a]pyridine-6-carboxamide |
| Formula | C22H26N4O3 |
| Molecular Weight | 394.47 |
| Purity | >98 % |
| Description | H + ,K + -ATPase inhibitor (pIC 50 = 6 in human recombinant ion-leaky assays); more potent in acidic conditions. Highly selective for H + ,K + -ATPase in vitro ; displays no activity at Na + ,K + -ATPase. Also displays selectivity for H + ,K + -ATPase over a range of 50 receptors and ion channels (IC 50 > 10 μ M). Inhibits gastric acid secretion in rat and dog models. |
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