PF 9184

• Supplier: Tocris Bioscience
• Catalog: 3291
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 1221971-47-6
• Chemical Name: N-[3',4'-Dichloro(1,1'-biphenyl)-yl]-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide1,1-dioxide
• Formula: C21H14Cl2N2O4S
• Molecular Weight: 461.32
• Purity: >98 %
• Description: Potent microsomal prostaglandin E synthase 1 (mPGES-1) inhibitor (IC 50 values are 16.5 and 1080 nM for human and rat mPGES-1, respectively). Exhibits >6500-fold selectivity for mPGES-1 over COX-1 and COX-2. Inhibits IL-1 β -induced PGE 2 synthesis in vitro .

Product References

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