| Name | PF CBP1 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3923 |
| Prices | $229.00, $945.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Chemical Name | 5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole |
| Formula | C29H36N4O3 |
| Molecular Weight | 488.62 |
| Purity | >98 % |
| Description | Selective CBP/p300 bromodomain inhibitor (IC 50 values are 125 and 363 nM, respectively). Exhibits >100-fold selectivity for CBP over BRD4. Also exhibits selectivity over a panel of other bromodomains. Reduces LPS-induced IL-1 β , IL-6 and IFN- β expression in macrophages in vitro . Also downregulates RGS4 expression in primary cortical neurons in vitro . |
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