Phaclofen

• Supplier: Tocris Bioscience
• Catalog: 3140
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 114012-12-3
• Chemical Name: (RS)-3-Amino-2-(4-chlorophenyl)propylphosphonicacid
• Formula: C9H13ClNO3P
• Molecular Weight: 249.63
• Purity: >97 %
• Description: Selective GABA B antagonist. Phosphono analog of GABA B agonist baclofen (Cat. No. 0417).

Product References

Phaclofen: a peripheral and central baclofen antagonist. - Phaclofen: a peripheral and central baclofen antagonist.

Kerr DI, Ong J, Prager RH, Gynther BD, Curtis DR. Brain Res. 1987 Mar 3;405(1):150-4.

Comparison of antagonism by phaclofen of baclofen induced hyperpolarizations and - Comparison of antagonism by phaclofen of baclofen induced hyperpolarizations and

Hasuo H, Gallagher JP. Neurosci Lett. 1988 Mar 21;86(1):77-81.

Phaclofen: a GABAB blocker reduces long-duration inhibition in the neocortex. - Phaclofen: a GABAB blocker reduces long-duration inhibition in the neocortex.

Karlsson G, Pozza M, Olpe HR. Eur J Pharmacol. 1988 Apr 13;148(3):485-6.