Phenserine

• Supplier: Tocris Bioscience
• Catalog: 4578
• Prices: $139.00
• Sizes: 50 mg
• Cas Number: 101246-66-6
• Chemical Name: (3aS,8aR)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol5-(N-phenylcarbamate)
• Formula: C20H23N3O2
• Molecular Weight: 337.42
• Purity: >98 %
• Description: Physostigmine analog that inhibits acetylcholinesterase. Inhibits production of amyloid precursor protein (APP) and A β . Improves morris water maze performance of scopolamine-treated rats.

Product References

The cholinesterase inhibitor, phenserine, improves Morris water maze performance - The cholinesterase inhibitor, phenserine, improves Morris water maze performance

Janas AM, Cunningham SC, Duffy KB, Devan BD, Greig NH, Holloway HW, Yu QS, Markowska AL, Ingram DK, Spangler EL. Life Sci. 2005 Jan 21;76(10):1073-81.

Identification of novel small molecule inhibitors of amyloid precursor protein - Identification of novel small molecule inhibitors of amyloid precursor protein

Utsuki T, Yu QS, Davidson D, Chen D, Holloway HW, Brossi A, Sambamurti K, Lahiri DK, Greig NH, Giordano T. J Pharmacol Exp Ther. 2006 Aug;318(2):855-62. Epub 2006 May 11.

Phenserine. - Phenserine.

Klein J. Expert Opin Investig Drugs. 2007 Jul;16(7):1087-97.