Phlorizin

• Supplier: Tocris Bioscience
• Catalog: 2770
• Prices: $49.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 60-81-1
• Chemical Name: 1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone
• Formula: C21H24O10
• Molecular Weight: 436.41
• Purity: >99 %
• Description: Inhibitor of Na + -glucose cotransporters (SGLT). Produces renal glycosuria and blocks intestinal glucose absorption. Normalizes insulin sensitivity in diabetic rats.

Product References

Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to - Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to

Rossetti L, Smith D, Shulman GI, Papachristou D, DeFronzo RA. J Clin Invest. 1987 May;79(5):1510-5.

Renal Na(+)-glucose cotransporters. - Renal Na(+)-glucose cotransporters.

Wright EM. Am J Physiol Renal Physiol. 2001 Jan;280(1):F10-8.

Phlorizin: a review. - Phlorizin: a review.

Ehrenkranz JR, Lewis NG, Kahn CR, Roth J. Diabetes Metab Res Rev. 2005 Jan-Feb;21(1):31-8.