PHM 27 (human)

• Supplier: Tocris Bioscience
• Catalog: 4627
• Prices: $209.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 118025-43-7
• Formula: C135H214N34O40S
• Molecular Weight: 2985.44
• Description: Endogenous peptide product of human prepro-VIP and analog of porcine PHI-27; potent agonist for the human calcitonin receptor (EC 50 = 11 nM). Transgenic mice expressing the human VIP/PHM 27 gene in pancreatic β -islets display enhanced glucose-induced insulin secretion.

Product References

Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like - Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like

Itoh N, Obata K, Yanaihara N, Okamoto H. Nature. 1983 Aug 11-17;304(5926):547-9.

Transgenic mice overexpressing human vasoactive intestinal peptide (VIP) gene in - Transgenic mice overexpressing human vasoactive intestinal peptide (VIP) gene in

Kato I, Suzuki Y, Akabane A, Yonekura H, Tanaka O, Kondo H, Takasawa S, Yoshimoto T, Okamoto H. J Biol Chem. 1994 Aug 19;269(33):21223-8.

Discovery of novel peptide/receptor interactions: identification of PHM-27 as a - Discovery of novel peptide/receptor interactions: identification of PHM-27 as a

Ma JN, Currier EA, Essex A, Feddock M, Spalding TA, Nash NR, Brann MR, Burstein ES. Biochem Pharmacol. 2004 Apr 1;67(7):1279-84.