Name | Phorbol 12,13-dibutyrate |
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Supplier | Tocris Bioscience |
Catalog | 2080 |
Prices | $65.00 |
Sizes | 1 mg |
Function Type | Activator |
Cas Number | 37558-16-0 |
Chemical Name | (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1a,1b,4,4a,5,7a,7b,8,9,9a-Decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9,9a-diylbutanoicacidester |
Formula | C28H40O8 |
Molecular Weight | 504.61 |
Purity | >98 % |
Description | Protein kinase C activator. Induces contraction of vascular smooth muscle and inhibits MLC phosphatase (MLCP) in vascular smooth muscle. Activity does not alter intracellular Ca 2+ concentration. Also inhibits the activity of Na + ,K + ATPase in OK cells. |
Supplier Page | Shop |
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Sakai H, Kurihara Y, Hashimoto Y, Chiba Y, Misawa M. J Smooth Muscle Res. 2010;46(5):259-66.