Phrixotoxin 3

Name Phrixotoxin 3
Supplier Tocris Bioscience
Catalog 4466
Prices $255.00
Sizes 100 µg
Function Type Blocker
Cas Number 880886-00-0
Formula C176H269N51O48S6
Molecular Weight 4059.74
Description Potent blocker of voltage-gated sodium channels (IC 50 values are 0.6, 42, and 72 nM for Na V 1.2, Na V 1.3 and Na V 1.5 respectively). Blocks inward sodium currents in a voltage-dependent manner.
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Product References

Four novel tarantula toxins as selective modulators of voltage-gated sodium - Four novel tarantula toxins as selective modulators of voltage-gated sodium

Bosmans F, Rash L, Zhu S, Diochot S, Lazdunski M, Escoubas P, Tytgat J. Mol Pharmacol. 2006 Feb;69(2):419-29. Epub 2005 Nov 2.

Characterization of voltage-dependent calcium channel blocking peptides from the - Characterization of voltage-dependent calcium channel blocking peptides from the

Ono S, Kimura T, Kubo T. Toxicon. 2011 Sep 1;58(3):265-76.