| Name | PI 103 hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 0622 |
| Prices | $95.00, $199.00, $825.00 |
| Sizes | 1 mg, 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 371935-79-4 |
| Chemical Name | 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenolhydrochloride |
| Formula | C19H16N4O3.HCl |
| Molecular Weight | 384.82 |
| Purity | >98 % |
| Description | Inhibitor of DNA-PK, PI 3-kinase (p110 α ) and mTOR (IC 50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ~ 1000 and 2300 nM for DNA-PK, p110 α , mTORC1, PI 3-KC2 β , p110 δ , mTORC2, p110 β , p110 γ , ATR, ATM, PI 3-KC2 α and hsVPS34 respectively). Inhibits growth of human tumor xenografts in mice in vivo . Induces autophagosome formation in glioma cells. |
| Supplier Page | Shop |
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