PI 3065

Name PI 3065
Supplier Tocris Bioscience
Catalog 2930
Prices $215.00, $905.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 955977-50-1
Chemical Name 6-[[4-(Cyclopropylmethyl)-1-piperazinyl]methyl]-2-(5-fluoro-1H-indol-4-yl)-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine
Formula C27H31FN6OS
Molecular Weight 506.64
Purity >98 %
Description Potent and selective PI 3-kinase p110 δ inhibitor (IC 50 = 5 nM; K i = 1.5 nM). Exhibits >100-fold selectivity over p100 α , p100 γ and p100 β isoforms (IC 50 values are 600, 910, >10,000 nM, respectively). Attenuates 4TI tumor growth and metastasis in vivo .
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