Piperlongumine

Name Piperlongumine
Supplier Tocris Bioscience
Catalog 0763
Prices $169.00, $705.00
Sizes 10 mg, 50 mg
Cas Number 20069-09-4
Chemical Name 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone
Formula C17H19NO5
Molecular Weight 317.34
Purity >97 %
Description Induces cell death and increases the level of reactive oxygen species (ROS) in cancer cells with both wild-type and normal p53. Also inhibits the growth of spontaneous malignant breast tumors in mice. Displays little effect on normal cells. Rapidly depletes androgen receptor expression in human prostate cancer cells via a ROS-dependent, proteasome-mediated mechanism.
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