Pirenzepine dihydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2973
• Prices: $75.00
• Sizes: 100 mg
• Function Type: Antagonist
• Cas Number: 29868-97-1
• Chemical Name: 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-onedihydrochloride
• Formula: C19H21N5O2.2HCl
• Molecular Weight: 424.33
• Purity: >98 %
• Description: M 1 muscarinic receptor selective antagonist. Inverse agonist activity reported.

Product References

Pirenzepine distinguishes between different subclasses of muscarinic receptors. - Pirenzepine distinguishes between different subclasses of muscarinic receptors.

Hammer R, Berrie CP, Birdsall NJ, Burgen AS, Hulme EC. Nature. 1980 Jan 3;283(5742):90-2.

Pharmacological profile of selective muscarinic receptor antagonists on - Pharmacological profile of selective muscarinic receptor antagonists on

Doods HN, Entzeroth M, Ziegler H, Mayer N, Holzer P. Eur J Pharmacol. 1994 Mar 3;253(3):275-81.

Muscarinic receptor subtypes and smooth muscle function. - Muscarinic receptor subtypes and smooth muscle function.

Eglen RM, Hegde SS, Watson N. Pharmacol Rev. 1996 Dec;48(4):531-65.

Inverse agonist activity of pirenzepine at M2 muscarinic acetylcholine receptors. - Inverse agonist activity of pirenzepine at M2 muscarinic acetylcholine receptors.

Daeffler L, Schmidlin F, Gies JP, Landry Y. Br J Pharmacol. 1999 Mar;126(5):1246-52.