PIT

• Supplier: Tocris Bioscience
• Catalog: 0960
• Prices: $115.00, $485.00
• Sizes: 10 mg, 50 mg
• Cas Number: 56583-49-4
• Chemical Name: 2-(2-Pyridinyl)-(3H)-indol-3-one-1-oxide4-methylbenzenesulfonate
• Formula: C13H8N2O2.C7H8O3S
• Molecular Weight: 396.42
• Purity: >99 %
• Description: Purinergic P2Y receptor ligand. Displays irreversible antagonism at P2Y receptors in some smooth muscles but potentiates responses to ATP in other systems (chick brain recombinant P2Y 1 receptor and sympathetic/purinergic nerve stimulation).

Product References

Antagonism of adenosine 5'-triphosphate-induced relaxation by - Antagonism of adenosine 5'-triphosphate-induced relaxation by

Spedding M, Sweetman AJ, Weetman DF. Br J Pharmacol. 1975 Apr;53(4):575-83.

Potentiation by 2,2'-pyridylisatogen tosylate of ATP-responses at a recombinant - Potentiation by 2,2'-pyridylisatogen tosylate of ATP-responses at a recombinant

King BF, Dacquet C, Ziganshin AU, Weetman DF, Burnstock G, Vanhoutte PM, Spedding M. Br J Pharmacol. 1996 Mar;117(6):1111-8.

Prominent sympathetic purinergic vasoconstriction in the rabbit splenic artery: - Prominent sympathetic purinergic vasoconstriction in the rabbit splenic artery:

Ren LM, Burnstock G. Br J Pharmacol. 1997 Feb;120(3):530-6.