| Name | PIT 1 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1682 |
| Prices | $155.00, $645.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 53501-41-0 |
| Chemical Name | N-[[(3-Chloro-2-hydroxy-5-nitrophenyl)amino]thioxomethyl]benzamide |
| Formula | C14H10ClN3O4S |
| Molecular Weight | 351.76 |
| Purity | >99 % |
| Description | Selective PIP 3 antagonist. Blocks the binding of PIP 3 to the pleckstrin homology (PH) domain of Akt (IC 50 = 31.03 μ M). Inhibits cancer cell survival and induces apoptosis by inhibition of PIP 3 -dependent PI 3-kinase/Akt signaling. Exhibits antitumor activity in vivo . |
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