PK 11195

• Supplier: Tocris Bioscience
• Catalog: 3255
• Prices: $89.00, $375.00
• Sizes: 10 mg, 50 mg
• Cas Number: 85532-75-8
• Chemical Name: 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
• Formula: C21H21ClN2O
• Molecular Weight: 352.86
• Purity: >98 %
• Description: Possesses high affinity for the peripheral benzodiazepine receptor (PBR, TSPO) without binding to other known neurotransmitter receptors. Also inhibits the human constitutive androstane receptor (hCAR).

Product References

Differentiation between two ligands for peripheral benzodiazepine binding sites, - Differentiation between two ligands for peripheral benzodiazepine binding sites,

Le Fur G, Vaucher N, Perrier ML, Flamier A, Benavides J, Renault C, Dubroeucq MC, Gueremy C, Uzan A. Life Sci. 1983 Aug 1;33(5):449-57.

Temporal changes in glial fibrillary acidic protein messenger RNA and [3H]PK11195 - Temporal changes in glial fibrillary acidic protein messenger RNA and [3H]PK11195

Conway EL, Gundlach AL, Craven JA. Neuroscience. 1998 Feb;82(3):805-17.

The peripheral benzodiazepine receptor ligand - The peripheral benzodiazepine receptor ligand

Li L, Chen T, Stanton JD, Sueyoshi T, Negishi M, Wang H. Mol Pharmacol. 2008 Aug;74(2):443-53.