4-PPBP maleate

Name 4-PPBP maleate
Supplier Tocris Bioscience
Catalog 1466
Prices $129.00, $535.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 201216-39-9
Chemical Name 4-Phenyl-1-(4-phenylbutyl)piperidinemaleate
Formula C21H27N.C4H4O4
Molecular Weight 409.52
Purity >99 %
Description σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes.
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Product References

Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity - Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity

Glennon RA, Yousif MY, Ismaiel AM, el-Ashmawy MB, Herndon JL, Fischer JB, Server AC, Howie KJ. J Med Chem. 1991 Dec;34(12):3360-5.

Antagonism of N-methyl-D-aspartate receptors by sigma site ligands: potency, - Antagonism of N-methyl-D-aspartate receptors by sigma site ligands: potency,

Whittemore ER, Ilyin VI, Woodward RM. J Pharmacol Exp Ther. 1997 Jul;282(1):326-38.