Prazosin hydrochloride

Name Prazosin hydrochloride
Supplier Tocris Bioscience
Catalog 2318
Prices $95.00
Sizes 100 mg
Function Type Antagonist
Cas Number 19237-84-4
Chemical Name 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazinehydrochloride
Formula C19H21N5O4.HCl
Molecular Weight 419.87
Purity >99 %
Description α 1 and α 2B -adrenoceptor antagonist. Also a potent antagonist at the melatonin MT 3 receptor (K i = 10.2 nM). Also available as part of the α 1 -Adrenoceptor Tocriset™ and Mixed Adrenergic Tocriset™ .
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Product References

Pharmacological characterization of melatonin binding sites in Syrian hamster - Pharmacological characterization of melatonin binding sites in Syrian hamster

Pickering DS, Niles LP. Eur J Pharmacol. 1990 Jan 3;175(1):71-7.

Prazosin inhibits MK-801-induced hyperlocomotion and dopamine release in the - Prazosin inhibits MK-801-induced hyperlocomotion and dopamine release in the

Mathe JM, Nomikos GG, Hildebrand BE, Hertel P, Svensson TH. Eur J Pharmacol. 1996 Aug 1;309(1):1-11.

Characterization of 2-[125I]iodomelatonin binding sites in Syrian hamster - Characterization of 2-[125I]iodomelatonin binding sites in Syrian hamster

Paul P, Lahaye C, Delagrange P, Nicolas JP, Canet E, Boutin JA. J Pharmacol Exp Ther. 1999 Jul;290(1):334-40.