Pregabalin

Name Pregabalin
Supplier Tocris Bioscience
Catalog 0589
Prices $175.00, $709.00
Sizes 10 mg, 50 mg
Cas Number 148553-50-8
Chemical Name (S)-3-(Aminomethyl)-5-methylhexanoicacid
Formula C8H17NO2
Molecular Weight 159.23
Description Anticonvulsant and antiepileptic; also used to treat neuropathic pain. Binds with high affinity and selectivity to the α 2 δ subunit of voltage-sensitive Ca 2+ channels and modulates their activity. Displays anxiolytic-like activity in ethological and conflict models of anxiety. Analog of GABA (Cat. No. 0344).
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Product References

Pregabalin may represent a novel class of anxiolytic agents with a broad spectrum - Pregabalin may represent a novel class of anxiolytic agents with a broad spectrum

Field MJ, Oles RJ, Singh L. Br J Pharmacol. 2001 Jan;132(1):1-4.

Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal - Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal

Kumar N, Laferriere A, Yu JS, Leavitt A, Coderre TJ. J Neurochem. 2010 Apr;113(2):552-61.