Prosaptide TX14(A)

Name Prosaptide TX14(A)
Supplier Tocris Bioscience
Catalog 1200
Prices $159.00
Sizes 1 mg
Function Type Agonist
Cas Number 196391-82-9
Formula C69H110N16O26
Molecular Weight 1579.72
Description Potent GPR37L1 and GPR37 agonist (EC 50 values are 5 and 7 nM, respectively). Stimulates signaling through pertussis toxin-sensitive G proteins. Stimulates ERK phosphorylation. Protects against cellular stress. Promotes myelin lipid synthesis and prolongs cell survival in both Schwann cells and oligodendrocytes; neuroprotective and glioprotective.
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Product References

Cell death prevention, mitogen-activated protein kinase stimulation, and - Cell death prevention, mitogen-activated protein kinase stimulation, and

Hiraiwa M, Taylor EM, Campana WM, Darin SJ, O'Brien JS. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4778-81.

GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective - GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective

Meyer RC, Giddens MM, Schaefer SA, Hall RA. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9529-34. doi: