Prostratin

Name Prostratin
Supplier Tocris Bioscience
Catalog 2306
Prices $99.00
Sizes 1 mg
Function Type Activator
Cas Number 60857-08-1
Chemical Name (1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one
Formula C22H30O6
Molecular Weight 390.47
Purity >98 %
Description PKC activator. Inhibits growth and induces differentiation of AML cell lines. Enhances cytarabine -induced differentiation of AML cells. Inhibits tumorigenesis in KRAS mutant pancreatic cancer cells and reduces tumor growth in mouse pancreatic tumor models. Also NF- κ B activator. Activates HIV gene expression in T cells. Orally available.
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