| Name | PT 1 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4367 |
| Prices | $195.00, $805.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Activator |
| Cas Number | 331002-70-1 |
| Chemical Name | 2-Chloro-5-[[5-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-4-oxo-2-thiazolyl]amino]benzoicacid |
| Formula | C23H16ClN3O6S |
| Molecular Weight | 497.91 |
| Purity | >98 % |
| Description | AMP-activated protein kinase (AMPK) activator. Stimulates AMPK heterotrimer ( α 1 β 1 γ 1) activity (EC 50 = 0.3 μ M). Selectively increases the activity of γ 1- but not γ 3-containing complexes. Thought to directly activate AMPK by antagonizing autoinhibition. |
| Supplier Page | Shop |
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Jensen TE, Ross FA, Kleinert M, Sylow L, Knudsen JR, Gowans GJ, Hardie DG, Richter EA. Biochem J. 2015 May 1;467(3):461-72.