Purotoxin 1

• Supplier: Tocris Bioscience
• Catalog: 4089
• Prices: $265.00
• Sizes: 100 µg
• Function Type: Modulator
• Cas Number: 1396322-38-5
• Formula: C155H249N51O47S8
• Molecular Weight: 3835.47
• Description: Potent P2X 3 receptor modulator (IC 50 = 12 nM). Exhibits negligible effects on P2X 2 and P2X 2/3 . Demonstrates antinociceptive properties in an animal model of inflammatory pain.

Product References

Novel peptide from spider venom inhibits P2X3 receptors and inflammatory pain. - Novel peptide from spider venom inhibits P2X3 receptors and inflammatory pain.

Grishin EV, Savchenko GA, Vassilevski AA, Korolkova YV, Boychuk YA, Viatchenko-Karpinski VY, Nadezhdin KD, Arseniev AS, Pluzhnikov KA, Kulyk VB, Voitenko NV, Krishtal OO. Ann Neurol. 2010 May;67(5):680-3.

Modulation of P2X3 receptors by spider toxins. - Modulation of P2X3 receptors by spider toxins.

Kabanova NV, Vassilevski AA, Rogachevskaja OA, Bystrova MF, Korolkova YV, Pluzhnikov KA, Romanov RA, Grishin EV, Kolesnikov SS. Biochim Biophys Acta. 2012 Nov;1818(11):2868-75. doi: