| Name | Pyr3 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2978 |
| Prices | $169.00, $705.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 1160514-60-2 |
| Chemical Name | 1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid |
| Formula | C16H11Cl3F3N3O3 |
| Molecular Weight | 456.63 |
| Purity | >98 % |
| Description | Selective antagonist of the canonical transient receptor potential channel 3 (TRPC3). Inhibits TRPC3-mediated Ca 2+ influx (IC 50 = 0.7 μ M) and suppresses activation of nuclear factor of activated T cells (NFAT). Inhibits hypertrophic responses in cardiomyocytes. |
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