PYZD 4409

Name PYZD 4409
Supplier Tocris Bioscience
Catalog 0727
Prices $199.00, $825.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 423148-78-1
Chemical Name 1-(3-Chloro-4-fluorophenyl)-4-[(5-nitro-2-furanyl)methylene]-3,5-pyrazolidinedione
Formula C14H7ClFN3O5
Molecular Weight 351.67
Purity >98 %
Description Ubiquitin-activating enzyme (E1) inhibitor. Blocks degradation of p53 and cyclin D3. Inhibits NF- κ B activation and induces cell death associated with ER stress. Displays antitumor effects in a mouse model of leukemia.
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