QAQ dichloride

Name QAQ dichloride
Supplier Tocris Bioscience
Catalog 4755
Prices $185.00, $755.00
Sizes 10 mg, 50 mg
Function Type Blocker
Chemical Name 2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium]dichloride
Formula C28H44Cl2N6O2
Molecular Weight 567.59
Purity >98 %
Description Photoswitchable Na v , Ca v and K v channel blocker. Blocks channels in the trans conformation. Switches conformation from cis to trans at 500 nm and trans to cis at 380 nm. Normally membrane impermeant, but enters nociceptive neurons via ion channels activated by noxious stimuli, particularly TRPV1. Exhibits optically reversible local anesthesia in rats.
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