Quin C1

• Supplier: Tocris Bioscience
• Catalog: 4735
• Prices: $175.00, $709.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 786706-21-6
• Chemical Name: 4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide
• Formula: C26H27N3O4
• Molecular Weight: 445.51
• Purity: >98 %
• Description: Potent and selective FPR2 agonist (EC 50 = 40 nM). Induces Ca 2+ mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro . Reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model. Anti-inflammatory.

Product References

Preclinical studies on quinelorane, a potent and highly selective D2-dopaminergic - Preclinical studies on quinelorane, a potent and highly selective D2-dopaminergic

Foreman MM, Fuller RW, Hynes MD, Gidda JS, Nichols CL, Schaus JM, Kornfeld EC, Clemens JA. J Pharmacol Exp Ther. 1989 Jul;250(1):227-35.

Effects of the selective dopaminergic D2 agonist quinelorane on the activity of - Effects of the selective dopaminergic D2 agonist quinelorane on the activity of

Eaton MJ, Lookingland KJ, Moore KE. J Pharmacol Exp Ther. 1994 Feb;268(2):645-52.

Comparison of D2 and D3 dopamine receptor affinity of dopaminergic compounds in - Comparison of D2 and D3 dopamine receptor affinity of dopaminergic compounds in

Flietstra RJ, Levant B. Life Sci. 1998;62(20):1825-31.