| Name | R 1530 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4964 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 882531-87-5 |
| Chemical Name | 5-(2-Chlorophenyl)-7-fluoro-1,2-dihydro-8-methoxy-3-methylpyrazolo[3,4-b][1,4]benzodiazepine |
| Formula | C18H14ClFN4O |
| Molecular Weight | 356.78 |
| Purity | >98 % |
| Description | Multi-kinase inhibitor. Exhibits inhibitory activity against Chk2, KDR, FGFR, Aurora A kinase and Cdk2 (IC 50 values are 24, 34, 50, 58 and 88 nM respectively). Also binds VEGFR-2, FGFR1 and PDGFR β (K d values are 0.015, 0.061 and 0.088 μ M respectively). Displays antiproliferative activity in vitro ; inhibits mitosis and angiogenesis. Orally bioavailable. |
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