| Name | R8-T198wt |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1577 |
| Prices | $95.00 |
| Sizes | 1 mg |
| Function Type | Inhibitor |
| Formula | C111H211N59O26S |
| Molecular Weight | 2820.33 |
| Description | Cell-permeable peptide inhibitor of Pim-1 kinase, derived from p27 Kip1 . Inhibits Pim-1 phosphorylation of p27 Kip1 and Bad; induces cell cycle arrest (at G 1 ) and apoptosis in DU145 prostate cancer cells. Also inhibits Pim-1-dependent growth of DU145 cells in vitro and in vivo . Displays no effect on the growth of normal prostate epithelial RPWE-1 cells at concentrations of 10 and 20 μ M. |
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