Rauwolscine hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 4308
• Prices: $75.00
• Sizes: 100 mg
• Function Type: Antagonist
• Cas Number: 6211-32-1
• Chemical Name: 17α-Hydroxy-20α-yohimban-16β-carboxylicacid,methylesterhydrochloride
• Formula: C21H26N2O3.HCl
• Molecular Weight: 390.91
• Purity: >95 %
• Description: Standard α 2 -adrenergic antagonist (K i values are 3.5, 4.6, and 0.6 nM at cloned human α 2A , α 2B , and α 2C -adrenoceptors respectively). Partial agonist at 5-HT 1A receptors. Also available as part of the α 2 -Adrenoceptor Tocriset™ . Diastereomer Yohimbine hydrochloride (Cat. No. 1127) also available.

Product References

Partial agonist properties of rauwolscine and yohimbine for the inhibition of - Partial agonist properties of rauwolscine and yohimbine for the inhibition of

Arthur JM, Casanas SJ, Raymond JR. Biochem Pharmacol. 1993 Jun 9;45(11):2337-41.

Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology - Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology

Hieble JP, Bondinell WE, Ruffolo RR Jr. J Med Chem. 1995 Sep 1;38(18):3415-44.

[3H]RS79948-197 binding to human, rat, guinea pig and pig alpha2A-, alpha2B- and - [3H]RS79948-197 binding to human, rat, guinea pig and pig alpha2A-, alpha2B- and

Uhlen S, Dambrova M, Nasman J, Schioth HB, Gu Y, Wikberg-Matsson A, Wikberg JE. Eur J Pharmacol. 1998 Feb 5;343(1):93-101.