RC 160

Name RC 160
Supplier Tocris Bioscience
Catalog 5411
Prices $129.00
Sizes 1 mg
Cas Number 103222-11-3
Formula C57H70N12O9S2
Molecular Weight 1131.37
Description Cyclic octapeptide somatostatin analog (K i values are 0.7, 5.4, 30.9, 45 and > 1000 nM for sst 5 , sst 2 , sst 3 , sst 4 and sst 1 receptors respectively). More metabolically stable than somatostatin (Cat. No. 1157). Inhibits growth hormone release in vivo .
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Product References

Effects of highly potent octapeptide analogs of somatostatin on growth hormone, - Effects of highly potent octapeptide analogs of somatostatin on growth hormone,

Karashima T, Cai RZ, Schally AV. Life Sci. 1987 Aug 24;41(8):1011-9.

Subtype selectivity of peptide analogs for all five cloned human somatostatin - Subtype selectivity of peptide analogs for all five cloned human somatostatin

Patel YC, Srikant CB. Endocrinology. 1994 Dec;135(6):2814-7.

sst2 Somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and - sst2 Somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and

Lahlou H, Saint-Laurent N, Esteve JP, Eychene A, Pradayrol L, Pyronnet S, Susini C. J Biol Chem. 2003 Oct 10;278(41):39356-71. Epub 2003 Jul 22.