Reboxetine mesylate

• Supplier: Tocris Bioscience
• Catalog: 3139
• Prices: $185.00, $755.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 98769-84-7
• Chemical Name: (2R*)-2-[(R*)-(2-Ethoxyphenoxy)phenylmethyl]morpholinemesylate
• Formula: C19H23NO3.CH3SO3H
• Molecular Weight: 409.5
• Purity: >99 %
• Description: Potent and selective inhibitor of noradrenalin uptake (K i values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). Displays > 1000-fold selectivity over α -adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active antidepressant.

Product References

Studies on the acute and chronic effects of reboxetine on extracellular - Studies on the acute and chronic effects of reboxetine on extracellular

Sacchetti G, Bernini M, Bianchetti A, Parini S, Invernizzi RW, Samanin R. Br J Pharmacol. 1999 Nov;128(6):1332-8.

Reboxetine: a pharmacologically potent, selective, and specific norepinephrine - Reboxetine: a pharmacologically potent, selective, and specific norepinephrine

Wong EH, Sonders MS, Amara SG, Tinholt PM, Piercey MF, Hoffmann WP, Hyslop DK, Franklin S, Porsolt RD, Bonsignori A, Carfagna N, McArthur RA. Biol Psychiatry. 2000 May 1;47(9):818-29.

S33005, a novel ligand at both serotonin and norepinephrine transporters: I. - S33005, a novel ligand at both serotonin and norepinephrine transporters: I.

Millan MJ, Gobert A, Lejeune F, Newman-Tancredi A, Rivet JM, Auclair A, Peglion JL. J Pharmacol Exp Ther. 2001 Aug;298(2):565-80.

Reboxetine modulates norepinephrine efflux in the frontal cortex of the freely - Reboxetine modulates norepinephrine efflux in the frontal cortex of the freely

Owen JC, Whitton PS. Neurosci Lett. 2003 Sep 18;348(3):171-4.