Rec 15/2615 dihydrochloride

• Supplier: Tocris Bioscience
• Catalog: 1982
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 173059-17-1
• Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[[2-methoxy-6-(1-methylethyl)phenoxy]acetyl]piperazinedihydrochloride
• Formula: C26H33N5O5.2HCl
• Molecular Weight: 568.49
• Purity: >98 %
• Description: Selective α 1B -adrenoceptor antagonist (K i values are 0.3, 1.9 and 2.6 nM at human α 1B , α 1A and α 1D receptors respectively).

Product References

Pharmacological characterization of the uroselective alpha-1 antagonist Rec - Pharmacological characterization of the uroselective alpha-1 antagonist Rec

Testa R, Guarneri L, Angelico P, Poggesi E, Taddei C, Sironi G, Colombo D, Sulpizio AC, Naselsky DP, Hieble JP, Leonardi A. J Pharmacol Exp Ther. 1997 Jun;281(3):1284-93.

Ligand design for alpha1 adrenoceptor subtype selective antagonists. - Ligand design for alpha1 adrenoceptor subtype selective antagonists.

Bremner JB, Coban B, Griffith R, Groenewoud KM, Yates BF. Bioorg Med Chem. 2000 Jan;8(1):201-14.

Alpha(1A)-adrenoceptors mediate contractions to phenylephrine in rabbit penile - Alpha(1A)-adrenoceptors mediate contractions to phenylephrine in rabbit penile

Morton JS, Daly CJ, Jackson VM, McGrath JC. Br J Pharmacol. 2007 Jan;150(1):112-20. Epub 2006 Nov 20.