Repaglinide

• Supplier: Tocris Bioscience
• Catalog: 0916
• Prices: $139.00
• Sizes: 50 mg
• Function Type: Blocker
• Cas Number: 135062-02-1
• Chemical Name: 2-Ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoicacid
• Formula: C27H36N2O4
• Molecular Weight: 452.59
• Purity: >99 %
• Description: K ir 6 (K ATP ) channel blocker that binds with high affinity for SUR1 when co-expressed with K ir 6.2 (K d = 0.42 nM). Antidiabetic glucose regulator with hypoglycaemic effect in vivo .

Product References

Hypoglycaemic effects of the novel antidiabetic agent repaglinide in rats and - Hypoglycaemic effects of the novel antidiabetic agent repaglinide in rats and

Mark M, Grell W. Br J Pharmacol. 1997 Aug;121(8):1597-604.

Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP) channels. - Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP) channels.

Hansen AM, Hansen JB, Carr RD, Ashcroft FM, Wahl P. Br J Pharmacol. 2005 Feb;144(4):551-7.