Reserpine

Name Reserpine
Supplier Tocris Bioscience
Catalog 3742
Prices $129.00
Sizes 1 g
Cas Number 50-55-5
Chemical Name (3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylicacidmethylester
Formula C33H40N2O9
Molecular Weight 608.68
Purity >99 %
Description Binds the vesicular monoamine transporter (VMAT2) and inhibits transport of biogenic amines into adrenal chromaffin granules and synaptic vesicles. Causes depletion of biogenic amine stores. Antihypertensive and antipsychotic.
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Product References

Reserpine binding to a vesicular amine transporter expressed in Chinese hamster - Reserpine binding to a vesicular amine transporter expressed in Chinese hamster

Schuldiner S, Liu Y, Edwards RH. J Biol Chem. 1993 Jan 5;268(1):29-34.

Effect of reserpine on behavioural responses to agonists at 5-HT1A, 5-HT1B, - Effect of reserpine on behavioural responses to agonists at 5-HT1A, 5-HT1B,

Heslop KE, Curzon G. Neuropharmacology. 1999 Jun;38(6):883-91.

Inhibitory effect of reserpine on dopamine transporter function. - Inhibitory effect of reserpine on dopamine transporter function.

Metzger RR, Brown JM, Sandoval V, Rau KS, Elwan MA, Miller GW, Hanson GR, Fleckenstein AE. Eur J Pharmacol. 2002 Dec 5;456(1-3):39-43.