Resiniferatoxin

• Supplier: Tocris Bioscience
• Catalog: 2742
• Prices: $149.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 57444-62-9
• Chemical Name: 4-Hydroxy-3-methoxy-[(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]benzeneacetate
• Formula: C37H40O9
• Molecular Weight: 628.72
• Purity: >98 %
• Description: Potent analog of capsaicin that is an agonist at vanilloid receptors (K i = 43 pM). Like capsaicin, it acts as a selective modulator of primary afferent neurons. Also available as part of the Vanilloid TRPV1 Receptor Tocriset™ .

Product References

Resiniferatoxin: an ultrapotent selective modulator of capsaicin-sensitive - Resiniferatoxin: an ultrapotent selective modulator of capsaicin-sensitive

Szolcsanyi J, Szallasi A, Szallasi Z, Joo F, Blumberg PM. J Pharmacol Exp Ther. 1990 Nov;255(2):923-8.

Cellular mechanism of action of resiniferatoxin: a potent sensory neuron - Cellular mechanism of action of resiniferatoxin: a potent sensory neuron

Winter J, Dray A, Wood JN, Yeats JC, Bevan S. Brain Res. 1990 Jun 18;520(1-2):131-40.

Distinct structure-activity relations for stimulation of 45Ca uptake and for high - Distinct structure-activity relations for stimulation of 45Ca uptake and for high

Acs G, Lee J, Marquez VE, Blumberg PM. Brain Res Mol Brain Res. 1996 Jan;35(1-2):173-82.