Name | Retigabine |
---|---|
Supplier | Tocris Bioscience |
Catalog | 3841 |
Prices | $79.00, $335.00 |
Sizes | 10 mg, 50 mg |
Function Type | Activator |
Cas Number | 150812-12-7 |
Chemical Name | Ethyl[2-amino-4-[[(4-fluorophenyl)methyl]amino]phenyl]carbamate |
Formula | C16H18FN3O2 |
Molecular Weight | 303.33 |
Purity | >98 % |
Description | K V 7 (KCNQ) channel activator (EC 50 values are 0.6 - 100 μ M for K V 7.1 - K V 7.5). Anticonvulsant. Orally bioavailable. |
Supplier Page | Shop |
Apfel C, Bauer F, Crettaz M, Forni L, Kamber M, Kaufmann F, LeMotte P, Pirson W, Klaus M. Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):7129-33.
Sanquer S, Gilchrest BA. Arch Biochem Biophys. 1994 May 15;311(1):86-94.
Dani C, Smith AG, Dessolin S, Leroy P, Staccini L, Villageois P, Darimont C, Ailhaud G. J Cell Sci. 1997 Jun;110 ( Pt 11):1279-85.
Stehlin-Gaon C, Willmann D, Zeyer D, Sanglier S, Van Dorsselaer A, Renaud JP, Moras D, Schule R. Nat Struct Biol. 2003 Oct;10(10):820-5. Epub 2003 Sep 7.