RFRP 3 (human)

• Supplier: Tocris Bioscience
• Catalog: 3672
• Prices: $139.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 311309-27-0
• Formula: C45H72N14O10
• Molecular Weight: 969.15
• Description: Agonist of the NPFF 1 receptor (IC 50 = 0.7 nM for inhibition of forskolin-induced cAMP production). Homolog of gonadotropin-inhibitory hormone (GnIH); inhibits activity of gonadotropin-releasing hormone (GnRH) neurons.

Product References

New neuropeptides containing carboxy-terminal RFamide and their receptor in - New neuropeptides containing carboxy-terminal RFamide and their receptor in

Hinuma S, Shintani Y, Fukusumi S, Iijima N, Matsumoto Y, Hosoya M, Fujii R, Watanabe T, Kikuchi K, Terao Y, Yano T, Yamamoto T, Kawamata Y, Habata Y, Asada M, Kitada C, Kurokawa T, Onda H, Nishimura O, Tanaka M, Ibata Y, Fujino M. Nat Cell Biol. 2000 Oct;2(10):703-8.

Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate - Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate

Ubuka T, Morgan K, Pawson AJ, Osugi T, Chowdhury VS, Minakata H, Tsutsui K, Millar RP, Bentley GE. PLoS One. 2009 Dec 22;4(12):e8400.

RFamide-related peptide-3 receptor gene expression in GnRH and kisspeptin neurons - RFamide-related peptide-3 receptor gene expression in GnRH and kisspeptin neurons

Rizwan MZ, Poling MC, Corr M, Cornes PA, Augustine RA, Quennell JH, Kauffman AS, Anderson GM. Endocrinology. 2012 Aug;153(8):3770-9.