Name | RHPS 4 methosulfate |
---|---|
Supplier | Tocris Bioscience |
Catalog | 5003 |
Prices | $189.00, $765.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 390362-78-4 |
Chemical Name | 3,11-Difluoro-6,8,13-trimethylquino[4,3,2-kl]acridiniummethylsulfate |
Formula | C22H17F2N2.CH3O4S |
Molecular Weight | 458.48 |
Purity | >98 % |
Description | Telomerase inhibitor. Inhibits growth of medulloblastoma and glioblastoma cells in vitro . Induces telomere injury and apoptosis, and reduces growth in CG5 breast cancer cell xenografts in mice. |
Supplier Page | Shop |
Kentsis A, Topisirovic I, Culjkovic B, Shao L, Borden KL. Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):18105-10. Epub 2004 Dec 15.
Assouline S, Culjkovic B, Cocolakis E, Rousseau C, Beslu N, Amri A, Caplan S, Leber B, Roy DC, Miller WH Jr, Borden KL. Blood. 2009 Jul 9;114(2):257-60.