Risedronate

• Supplier: Tocris Bioscience
• Catalog: 1497
• Prices: $105.00
• Sizes: 50 mg
• Cas Number: 115436-72-1
• Chemical Name: P,P'-[1-Hydroxy-2-(3-pyridonyl)ethylidene]bis-phosphonicacidsodiumsalt
• Formula: C7H10NNaO7P2
• Molecular Weight: 305.09
• Purity: >99 %
• Description: Orally active biphosphonate that inhibits farnesyl diphosphate (FPP) synthase (IC 50 = 100 nM). Exhibits antiproliferative and proapoptotic activity in numerous tumor cell lines and inhibits osteoclast-mediated bone resorption in vivo .

Product References

Recent advances in understanding the mechanism of action of bisphosphonates. - Recent advances in understanding the mechanism of action of bisphosphonates.

Coxon FP, Thompson K, Rogers MJ. Curr Opin Pharmacol. 2006 Jun;6(3):307-12. Epub 2006 May 2.

Lowering bone mineral affinity of bisphosphonates as a therapeutic strategy to - Lowering bone mineral affinity of bisphosphonates as a therapeutic strategy to

Fournier PG, Daubine F, Lundy MW, Rogers MJ, Ebetino FH, Clezardin P. Cancer Res. 2008 Nov 1;68(21):8945-53.